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تاثیر رفتار غیرنیوتنی بر انتقال ذرات لیپوپروتیئن کم دانسیته ناحیه ورتکسی در رگ کاروتید انسانی | ||
| نشریه مهندسی مکانیک امیرکبیر | ||
| مقاله 3، دوره 53، شماره 9، آذر 1400، صفحه 4789-4806 اصل مقاله (2.57 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22060/mej.2021.19068.6946 | ||
| نویسندگان | ||
| آرام پیری1؛ ساجد هادی بافکر2؛ ایرج میرزایی* 3؛ نادر پورمحمود حصار4؛ حسن شیروانی5 | ||
| 1گروه مهندسی مکانیک، فنی و مهندسی، دانشگاه ارومیه، ارومیه، ایران | ||
| 2گروه مهندسی مکانیک دانشکده فنی و مهندسی دانشگاه ارومیه ارومیه ایران | ||
| 3دانشگاه ارومیه*دانشکده فنی و مهندسی | ||
| 4استاد، دانشکده مهندسی مکانیک، دانشگاه ارومیه، ارومیه، ایران | ||
| 5استاد، دانشکده مهندسی مکانیک، دانشگاه راسکین انگلستان | ||
| چکیده | ||
| رگ کاروتید به دلیل شرایط خاص هندسی، مستعد تشکیل جریان چرخشی و نوسانات جریانی است. دراینمقالههندسه رگ کاروتید حاضر از تصاویر حاصل از سی تی آنژیو یک فرد سالم ۱۹ ساله بدست آمده و مدل سازی عددیجریان آرام ناپایایخون بر روی آن انجام شده است. نتایج عمدتاً شامل تنش برشی، غلظت ذراتلیوپروتئین با دانسیته پایین است. ارزیابیهانشانمیدهد کهغلظتتخمینزدهشدهبهوسیلهمدلهایغیرنیوتنیبیش ازنتایجمدلنیوتنیاست. درصد اختلاف غلظت برای مدل کیسون و نیوتنی در شریان کاروتید مشترکحدود 12/5 درصد است.از طرفی براساس نتایج کمی و کیفی، دو قسمت حباب کاروتید و بخش ابتدایی کاروتید خارجی میزبان تشکیل نواحی بازچرخشی است که در این میان حباب کاروتید بیشترین حجم ناحیه ورتکسی را به خود اختصاص میدهد. البته روی هم رفته مدل نیوتنی حجم ناحیه بازچرخش را بیش از مدلهای غیرنیوتنی نشان میدهد. بر مبنای نتایج شبیهسازی، علی رغم پایین بودن مقدار فاکتور اهمیت غیرنیوتنی، به دلیل اثرات خواص غیرنیوتنی خون بر روی حجم ناحیه بازچرخش، اینگونه استباط میشودکه لحاظ خواص غیرنیوتنی خون حتی در عروق بزرگ نیز میتواند موجب حصول نتایج دقیقتر گردد. | ||
| کلیدواژهها | ||
| انتقال جرم؛ شریان کاروتید؛ غیرنیوتنی؛ جریان گذرا | ||
| عنوان مقاله [English] | ||
| The Effect of Non-Newtonian Behavior on the Transport of Low Density Lipoprotein Particles in the Vortex Region in the Human Carotid Artery | ||
| نویسندگان [English] | ||
| aram piri1؛ Sajed Hadi Bafekr2؛ Iraj Mirzaee3؛ Nader Pormahmod Hesar4؛ Hassan shirvani5 | ||
| 1Faculty of Mechanical Engineering, Urmia University, Urmia, Iran | ||
| 2Faculty of Mechanical Engineering, Urmia University | ||
| 3Faculty of Mechanical Engineering, Urmia, Iran | ||
| 4Professor, University of Urmia, Urmia, Iran | ||
| 5Faculty of Science & Technology, Anglia Ruskin University, Cambridge, UK | ||
| چکیده [English] | ||
| The common carotid artery is a large vessel which supplies oxygenated blood to the large front of the brain. The artery geometry is extracted from computed tomography angiography images of a healthy 20-year-old volunteer. ANSYS-Fluent commercial software is utilized to simulate the blood transient laminar flow in common, external and internal carotid arteries. In addition to the Newtonian viscosity model, two non-newtonian generalized power law and the modified Casson models have been selected for comparison. The quantitative and qualitative results include the distribution of the low density lipoprotein concentration, the wall shear stress and its fluctuations, and the volume and shape of the recirculation zone. Computations show that the low density lipoprotein Concentration estimated by non-Newtonian models is higher than by the Newtonian model. On the other hand, the carotid bulb and the beginning part of the external carotid artery, contain a large volume of the recirculation flow. Also, the low density lipoprotein particles concentration Comparison between the two modified Casson and Newtonian models in the common carotid artery zone shows the difference of about 12.5 percent. The results of this study show that the vortex region volume and shape are changed during the cardiac period cycle. The findings also reveal that Newtonian and non-Newtonian models present different results in predicting the flow parameters and secondary flow estimation. | ||
| کلیدواژهها [English] | ||
| Unsteady flow, Non-Newtonian, Carotid artery, Mass transport | ||
| مراجع | ||
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