پیوندهای مفید
آمار
| تعداد نشریات | 8 |
| تعداد شماره‌ها | 421 |
| تعداد مقالات | 5,525 |
| تعداد مشاهده مقاله | 6,356,380 |
| تعداد دریافت فایل اصل مقاله | 5,475,424 |
کنترل مود لغزشی اندازه قطرات در یک میکروکانال با تنظیم دبی پمپ تزریق: بررسی تجربی | ||
| نشریه مهندسی مکانیک امیرکبیر | ||
| مقاله 2، دوره 54، شماره 10، دی 1401، صفحه 2239-2254 اصل مقاله (2.81 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22060/mej.2022.20666.7290 | ||
| نویسندگان | ||
| علی اصغر مهدی زاده سولا؛ مصطفی نظری* ؛ حبیب احمدی؛ محسن نظری | ||
| دانشکده مهندسی مکانیک و مکاترونیک، دانشگاه صنعتی شاهرود، شاهرود، ایران | ||
| چکیده | ||
| امروزه در زمینه تولید میکروقطرات تحقیقات زیادی صورت‌گرفته است، اما تعداد محدودی از آن‌ها به کنترل فعال اندازه قطره و تغییر آن به‌صورت برخط پرداخته‌اند. در این تحقیق، ابتدا یک میکروکانال با هندسه جریان متمرکز شونده با استفاده از روش فوتولیتوگرافی ساخته شده است. جهت تزریق سیالات در درون کانال، یک پمپ تزریق با استفاده از یک موتور جریان مستقیم با دور و گشتاور مناسب و ماژول طراحی و ساخته شده است. سیالات مورد استفاده در این تحقیق، آب دو بار تقطیر به عنوان فاز گسسته و روغن به عنوان فاز پیوسته است. همچنین برای کنترل خودکار این سیستم، یک بورد آردوینو مگا 2560 به‌عنوان سیستم پردازنده استفاده شده است. قطر قطرات به کمک یک میکروسکوپ دیجیتال سرعت بالا و پردازش تصویر آن با یک روش پر سرعت محاسبه می‌‌شود. برای کنترل اندازه قطرات از دوحلقه کنترلی استفاده شده است؛ در حلقه داخلی جهت غلبه بر نامعینی‌ها از روش کنترل مود لغزشی، و در حلقه خارجی از کنترلکننده تناسبی-انتگرالگیر-مشتق‌گیر استفاده شده است. نتایج به‌دست‌آمده برای سه قطر متفاوت 82، 90 و 100 میکرومتر نشان دهنده عملکرد مناسب کنترلکننده طراحی شده است. عملکرد سیستم مدار بسته در هر حالت با ترسیم نمودار هیستوگرام ارزیابی شده است. | ||
| کلیدواژه‌ها | ||
| میکروسیال‌ها؛ میکروقطرات؛ پمپ تزریق؛ کنترل سایز قطرات؛ کنترلکننده مود لغزشی | ||
| عنوان مقاله [English] | ||
| Sliding Mode Control of Droplet Size in a Microchannel by Adjusting Syringe-Pump Flow: Experimental Study | ||
| نویسندگان [English] | ||
| Ali Asghar Mahdizadeh soula؛ Mostafa Nazari؛ Habib Ahmadi؛ Mohsen Nazari | ||
| Shahrood University of Technology | ||
| چکیده [English] | ||
| Microfluidics has many applications in modern sciences such as medicine and biomedical engineering. There are usually two ways of injecting fluids; using pressure regulations in fluid flow lines and using syringe pumps, which using syringe pumps is the most common way. Today, a lot of research has been done in this field, but a limited number of them have focused on active control of the droplet size. In this research, a microchannel was first fabricated using photolithography. To inject fluids into the channels, a syringe pump is designed and built using a DC motor with suitable speed and torque and the L298N module. The fluids used in this research are double distilled water as a discrete phase and oil as a continuous phase. An Arduino Mega 2560 board has also been used as the processor to automatically control this system. The droplet diameter is calculated using a digital microscope and its image processing with a high-speed algorithm. The sliding mode control algorithm has been used to control the droplet size due to the nonlinearity of the system behavior as well as the disturbances. The obtained results for three different diameters i.e. 82, 90, and 100 µm, show the accurate performance of the sliding mode controller. | ||
| کلیدواژه‌ها [English] | ||
| Microfluidics, Micro-droplets, Syringe pump, Droplet size control, Sliding mode control | ||
| مراجع | ||
|
[1] N.-T. Nguyen, G. Zhu, Y.-C. Chua, V.-N. Phan, S.-H. Tan, Magnetowetting and sliding motion of a sessile ferrofluid droplet in the presence of a permanent magnet, Langmuir, 26(15) (2010) 12553-12559. [2] A.G. Hadd, S.C. Jacobson, J.M. Ramsey, Microfluidic assays of acetylcholinesterase inhibitors, Analytical Chemistry, 71(22) (1999) 5206-5212. [3] E. Lagally, I. Medintz, R. Mathies, Single-molecule DNA amplification and analysis in an integrated microfluidic device, Analytical chemistry, 73(3) (2001) 565-570. [4] Z.Z. Chong, S.H. Tan, A.M. Gañán-Calvo, S.B. Tor, N.H. Loh, N.-T. Nguyen, Active droplet generation in microfluidics, Lab on a Chip, 16(1) (2016) 35-58. [5] P. Garstecki, M.J. Fuerstman, H.A. Stone, G.M. Whitesides, Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up, Lab on a Chip, 6(3) (2006) 437-446. [6] S.-H. Tan, N.-T. Nguyen, L. Yobas, T.G. Kang, Formation and manipulation of ferrofluid droplets at a microfluidic T-junction, Journal of Micromechanics and Microengineering, 20(4) (2010) 045004. [7] T. Thorsen, R.W. Roberts, F.H. Arnold, S.R. Quake, Dynamic pattern formation in a vesicle-generating microfluidic device, Physical review letters, 86(18) (2001) 4163. [8] S.L. Anna, N. Bontoux, H.A. Stone, Formation of dispersions using “flow focusing” in microchannels, Applied physics letters, 82(3) (2003) 364-366. [9] A.M. Gañán-Calvo, Generation of steady liquid microthreads and micron-sized monodisperse sprays in gas streams, Physical review letters, 80(2) (1998) 285. [10] M.A. Herrada, A.M. Gañán-Calvo, Swirl flow focusing: A novel procedure for the massive production of monodisperse microbubbles, Physics of Fluids, 21(4) (2009) 042003. [11] H. Kim, D. Luo, D. Link, D.A. Weitz, M. Marquez, Z. Cheng, Controlled production of emulsion drops using an electric field in a flow-focusing microfluidic device, Applied Physics Letters, 91(13) (2007) 133106. [12] F. Malloggi, H. Gu, A. Banpurkar, S. Vanapalli, F. Mugele, Electrowetting--A versatile tool for controlling microdrop generation, The European Physical Journal E, 26(1) (2008) 91-96. [13] N.-T. Nguyen, T.-H. Ting, Y.-F. Yap, T.-N. Wong, J.C.-K. Chai, W.-L. Ong, J. Zhou, S.-H. Tan, L. Yobas, Thermally mediated droplet formation in microchannels, Applied Physics Letters, 91(8) (2007) 084102. [14] S.-Y. Park, T.-H. Wu, Y. Chen, M.A. Teitell, P.-Y. Chiou, High-speed droplet generation on demand driven by pulse laser-induced cavitation, Lab on a Chip, 11(6) (2011) 1010-1012. [15] H. Willaime, V. Barbier, L. Kloul, S. Maine, P. Tabeling, Arnold tongues in a microfluidic drop emitter, Physical review letters, 96(5) (2006) 054501. [16] A. Bransky, N. Korin, M. Khoury, S. Levenberg, A microfluidic droplet generator based on a piezoelectric actuator, Lab on a Chip, 9(4) (2009) 516-520. [17] N. Pamme, Magnetism and microfluidics, Lab on a Chip, 6(1) (2006) 24-38. [18] J. Rife, M. Miller, P. Sheehan, C. Tamanaha, M. Tondra, L. Whitman, Design and performance of GMR sensors for the detection of magnetic microbeads in biosensors, Sensors and Actuators A: Physical, 107(3) (2003) 209-218. [19] C. Elbuken, T. Glawdel, D. Chan, C.L. Ren, Detection of microdroplet size and speed using capacitive sensors, Sensors and Actuators A: Physical, 171(2) (2011) 55-62. [20] H. Kim, D. Cheon, J. Lim, K. Nam, Robust Flow Control of a Syringe Pump Based on Dual-Loop Disturbance Observers, IEEE Access, 7 (2019) 135427-135438. [21] S. Motaghi, M. Nazari, M. Nazari, N. Sepehri, A. Mahdavi, Control of Droplet Size in a Two-Phase Microchannel using PID Controller: A Novel Experimental Study, Amirkabir Journal of Mechanical Engineering, 53 (7) (2021) 1-10. [22] H. Fu, W. Zeng, S. Li, S. Yuan, Electrical-detection droplet microfluidic closed-loop control system for precise droplet production, Sensors and Actuators A: Physical, 267 (2017) 142-149. [23] J.B. Christen, A.G. Andreou, Design, fabrication, and testing of a hybrid CMOS/PDMS microsystem for cell culture and incubation, IEEE Transactions on Biomedical Circuits and Systems, 1(1) (2007) 3-18. [24] E. Miller, M. Rotea, J.P. Rothstein, Microfluidic device incorporating closed loop feedback control for uniform and tunable production of micro-droplets, Lab on a Chip, 10(10) (2010) 1293-1301. [25] Y.J. Heo, J. Kang, W.K. Chung, Robust control for valveless flow switching in microfluidic networks, in: 2015 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), IEEE, 2015, pp. 1982-1987. [26] Y.J. Heo, J. Kang, M.J. Kim, W.K. Chung, Tuning-free controller to accurately regulate flow rates in a microfluidic network, Scientific reports, 6(1) (2016) 1-12. [27] Y. Kim, B. Kuczenski, P.R. LeDuc, W.C. Messner, Modulation of fluidic resistance and capacitance for long-term, high-speed feedback control of a microfluidic interface, Lab on a Chip, 9(17) (2009) 2603-2609. [28] D. Huang, K. Wang, Y. Wang, H. Sun, X. Liang, T. Meng, Precise control for the size of droplet in T-junction microfluidic based on iterative learning method, Journal of the Franklin Institute, 357(9) (2020) 5302-5316. [29] Y. Tang, Y. Chen, K. Wang, Y. Miao, A micro-vibrator based cross-junction microfluidic system for formation and control of droplets, in: Journal of Physics: Conference Series, IOP Publishing, 2021, pp. 012006. [30] Y. Xie, A.J. Dixon, J.R. Rickel, A.L. Klibanov, J.A. Hossack, Closed-loop feedback control of microbubble diameter from a flow-focusing microfluidic device, Biomicrofluidics, 14(3) (2020) 034101. [31] L. Li, Z. Gu, J.-L. Zhou, B. Yan, C. Kong, H. Wang, H.-F. Wang, Intelligent droplet tracking with correlation filters for digital microfluidics, Chinese Chemical Letters, 32(11) (2021) 3416-3420. [32] Z. Luo, B. Huang, J. Xu, L. Wang, Z. Huang, L. Cao, S. Liu, Machine vision-based driving and feedback scheme for digital microfluidics system, Open Chemistry, 19(1) (2021) 665-677. [33] A.M. Ibrahim, J.I. Padovani, R.T. Howe, Y.H. Anis, Modeling of Droplet Generation in a Microfluidic Flow-Focusing Junction for Droplet Size Control, Micromachines, 12(6) (2021) 590. [34] N. Shi, M. Mohibullah, C.J. Easley, Active Flow Control and Dynamic Analysis in Droplet Microfluidics, Annual Review of Analytical Chemistry, 14 (2021) 133-153. [35] J. Friend, L. Yeo, Fabrication of microfluidic devices using polydimethylsiloxane, Biomicrofluidics, 4(2) (2010) 026502. [36] P. Renaud, H. Van Lintel, M. Heuschkel, L. Guerin, Photo-polymer microchannel technologies and applications, Micro Total Analysis Systems’98, (1998) 17-22. [37] T. Kong, J. Wu, M. To, K. Wai Kwok Yeung, H. Cheung Shum, L. Wang, Droplet based microfluidic fabrication of designer microparticles for encapsulation applications, Biomicrofluidics, 6 (2012). [38] A.S. Basu, Droplet morphometry and velocimetry (DMV): a video processing software for time-resolved, label-free tracking of droplet parameters, Lab on a Chip, 13(10) (2013) 1892-1901. [39] S. Mottaghi, M. Nazari, S.M. Fattahi, M. Nazari, S. Babamohammadi, Droplet size prediction in a microfluidic flow focusing device using an adaptive network based fuzzy inference system, Biomedical Microdevices, 22(3) (2020) 1-12. [40] J.-J.E. Slotine, W. Li, Applied nonlinear control, Prentice hall Englewood Cliffs, NJ, 1991. | ||
|
آمار تعداد مشاهده مقاله: 442 تعداد دریافت فایل اصل مقاله: 641 |
||