Masoumii, N., . Bastani, D, Najarian, S., Farmanzad, F., Seddighi, A.M.. (1388). Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles. نشریه مهندسی عمران امیرکبیر, 41(1), 31-36. doi: 10.22060/eej.2009.275
N. Masoumii; D . Bastani; S. Najarian; F. Farmanzad; A.M. Seddighi. "Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles". نشریه مهندسی عمران امیرکبیر, 41, 1, 1388, 31-36. doi: 10.22060/eej.2009.275
Masoumii, N., . Bastani, D, Najarian, S., Farmanzad, F., Seddighi, A.M.. (1388). 'Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles', نشریه مهندسی عمران امیرکبیر, 41(1), pp. 31-36. doi: 10.22060/eej.2009.275
Masoumii, N., . Bastani, D, Najarian, S., Farmanzad, F., Seddighi, A.M.. Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles. نشریه مهندسی عمران امیرکبیر, 1388; 41(1): 31-36. doi: 10.22060/eej.2009.275

Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles

AUT Journal of Electrical Engineering
مقاله 4، دوره 41، شماره 1، 2009، صفحه 31-36    اصل مقاله (159.96 K)
نوع مقاله: Research Article
شناسه دیجیتال (DOI): 10.22060/eej.2009.275
نویسندگان
N. Masoumii1؛ D . Bastani2؛ S. Najarian3؛ F. Farmanzad4؛ A.M. Seddighi5
1N. Masoumi is with the Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran (e-mail: masoomy@mehr.sharif.edu)
2D. Bastani is with the Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran (e-mail: bastani@sharif.edu)
3S. Najarian is with the Robotic Surgery and Artificial Tactile Sensing Laboratory, Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (email: najarian@aut.ac.ir)
4F. Farmanzad is with the Department of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran (email: Farmanzad@iust.ac.ir)
5A. M. Seddighi is with the Medical Science Department, Shahid Beheshti University, Tehran, Iran (email: Invincible19152@gmail.com)
چکیده
In this article, dynamics of the cerebrospinal fluid (CSF) was studied, using computational fluid dynamics. Using MRI images of two special cases, a 2-dimensional model of the ventricular system was made. CSF velocity and pressure distribution in ventricular system have high importance since the flow pattern of this liquid has an important effect on intracranial pressure, i.e., ICP, which has a key role in treatment of patients suffering from brain trauma. The pulsatile nature of CSF production, which is a result of arterial blood pressure in choroid plexuses, is considered for the first time.  Finite element analysis of ventricular area with CFD analyzer software was processed using ADINA 8.2. Pressure distribution in different conditions of CSF production, i.e., constant input flow rate and pulsatile input flow rate, were compared. Comparison between the simulation results and reported experimental data depicted that modeling CSF with pulsatile production nature is more realistic. 
کلیدواژه‌ها
Cerebrospinal Fluid (CSF)؛ Intracranial pressure (ICP)؛ Aqueduct velocity؛ Hydrodynamic modeling
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