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Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles | ||
| AUT Journal of Electrical Engineering | ||
| مقاله 4، دوره 41، شماره 1، تیر 2009، صفحه 31-36 اصل مقاله (159.96 K) | ||
| نوع مقاله: Research Article | ||
| شناسه دیجیتال (DOI): 10.22060/eej.2009.275 | ||
| نویسندگان | ||
| N. Masoumii1؛ D . Bastani2؛ S. Najarian3؛ F. Farmanzad4؛ A.M. Seddighi5 | ||
| 1N. Masoumi is with the Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran (e-mail: masoomy@mehr.sharif.edu) | ||
| 2D. Bastani is with the Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran (e-mail: bastani@sharif.edu) | ||
| 3S. Najarian is with the Robotic Surgery and Artificial Tactile Sensing Laboratory, Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (email: najarian@aut.ac.ir) | ||
| 4F. Farmanzad is with the Department of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran (email: Farmanzad@iust.ac.ir) | ||
| 5A. M. Seddighi is with the Medical Science Department, Shahid Beheshti University, Tehran, Iran (email: Invincible19152@gmail.com) | ||
| چکیده | ||
| In this article, dynamics of the cerebrospinal fluid (CSF) was studied, using computational fluid dynamics. Using MRI images of two special cases, a 2-dimensional model of the ventricular system was made. CSF velocity and pressure distribution in ventricular system have high importance since the flow pattern of this liquid has an important effect on intracranial pressure, i.e., ICP, which has a key role in treatment of patients suffering from brain trauma. The pulsatile nature of CSF production, which is a result of arterial blood pressure in choroid plexuses, is considered for the first time. Finite element analysis of ventricular area with CFD analyzer software was processed using ADINA 8.2. Pressure distribution in different conditions of CSF production, i.e., constant input flow rate and pulsatile input flow rate, were compared. Comparison between the simulation results and reported experimental data depicted that modeling CSF with pulsatile production nature is more realistic. | ||
| کلیدواژه‌ها | ||
| Cerebrospinal Fluid (CSF)؛ Intracranial pressure (ICP)؛ Aqueduct velocity؛ Hydrodynamic modeling | ||
| عنوان مقاله [English] | ||
| Cerebrospinal Pulsation Hydrodynamics in a 2D Simulation of Brain Ventricles | ||
| چکیده [English] | ||
| In this article, dynamics of the cerebrospinal fluid (CSF) was studied, using computational fluid dynamics. Using MRI images of two special cases, a 2-dimensional model of the ventricular system was made. CSF velocity and pressure distribution in ventricular system have high importance since the flow pattern of this liquid has an important effect on intracranial pressure, i.e., ICP, which has a key role in treatment of patients suffering from brain trauma. The pulsatile nature of CSF production, which is a result of arterial blood pressure in choroid plexuses, is considered for the first time. Finite element analysis of ventricular area with CFD analyzer software was processed using ADINA 8.2. Pressure distribution in different conditions of CSF production, i.e., constant input flow rate and pulsatile input flow rate, were compared. Comparison between the simulation results and reported experimental data depicted that modeling CSF with pulsatile production nature is more realistic. | ||
| کلیدواژه‌ها [English] | ||
| Cerebrospinal Fluid (CSF), Intracranial pressure (ICP), Aqueduct velocity, Hydrodynamic modeling | ||
| مراجع | ||
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[1] Vaeze Mahdavi M.R., Takian, A.H., “Human Anatomy and Physilogy”, Shahed University Publication Company, (1997). [2] Ursino M., "A Mathematical Study of Human Intractranial Hydrodynamics PART1–The Cerebrospinal Fluid Pulse Pressure." Annals of Biomedical Engineering, 16 (1988): 379-401. [3] Jacobson E., Fletcher D.F., "Computer Modelling of the Cerebrospinal Fluid Flow Dynamics of Aqueduct Stenosis." Medical & Biological Engineering & Computing, 37 (1999): 59-63. [4] Loth F., Yardimci M.A., et al, "Hydrodynamic Modeling of Cerebrospinal Fluid Motion within the Spinal Cavity." Journal of Biomechanical Engineering—Transactions of the ASME 123, (2001): 71–79. [5] Kurtcuoglu V., Poulikakos D., et al, "Computational Modeling of the Mechanical Behavior of the Cerebrospinal Fluid System." Journal of Biomechanical Engineering, 127 (2005): 264-269. [6] Aroussi A., Howden L., et al, "3D Visualisation of Cerebrospinal Fluid Flow Within the Human Central Nervous." Journal of Flow Visualization and Image Processing, 13 (2006): 313-322. [7] Ammourah S., Aroussi A., et al, "Cerebrospinal Fluid Dynamics in a Simplified Model of the Human Ventricular System." 11th Annual Conference on CFD, Vancouver BC, Canada, (2003). 28-30. [8] Gibson A., Bayford R. H., et al, "Two-Dimensional Finite Element Modelling of the Neonatal Head." J. Physiology Measurment, 21 (2002): 45–52. [9] Egnor M., Zheng L., et al, "A Model of Pulsations in Communicating Hydrocephalus." J. Pediatric Neurosurg, 36 (2002): 281–303. [10] Madsen J.R., Egnor M., "Cerebrospinal Fluid Pulsatility and Hydrocephalus: The Fourth Circulation." Clinial Neurosurgery, 53 (2006): 48-52. [11] Kurtcuoglu V, Soellinger M., et al, "Computational Investigation of Subject-Specific Cerebrospinal Fluid." J. Biomechanics, 40 (2007): 1235–1245. [12] Linninger A.A., Xenos M., et al, "Cerebrospinal Fluid Flow in the Normal and Hydrocephalic Human Brain." IEEE Transactions on Biomedical Engineering, 54 (2007): 291-302. Linninger A.A., Tsakiris C., "Pulsatile Cerebrospinal Fluid Dynamics in the Human Brain." IEEE Transactions on Biomedical Engineering, 52 | ||
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